The main objective of the Action is to improve understanding, monitoring and control of lipid peroxidation in medicine and related biosciences and technologies. Secondary objectives – improve methods for detection and quantitation of lipid peroxidation for use in research and subsequent application (through biotechnology) to clinical science; – determine the prevalence of lipid peroxidation products in various inflammatory diseases and its correlation to disease severity or outcome; – elucidate the metabolism of important lipid peroxidation products and improve our understanding of their proinflammatory and other biological effects; – develop and test novel antioxidants that could have future applications in therapy for inflammatory diseases.